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10050 Sigma

Amygdalin

BioXtra, ≥97.0% (HPLC)

Synonym: D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside, D-Mandelonitrile-β-gentiobioside, Laetrile

  • CAS Number 29883-15-6

  • Empirical Formula (Hill Notation) C20H27NO11

  • Molecular Weight 457.43

  •  Beilstein Registry Number 66856

  •  EC Number 249-925-3

  •  MDL number MFCD00006598

  •  PubChem Substance ID 57646792

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C, Cell Biology,
InChI Key   XUCIJNAGGSZNQT-SWRVSKMJSA-N
product line   BioXtra
assay   ≥97.0% (HPLC)
optical activity   [α]20/D −39±2°, c = 2% in H2O
loss   ≤7.5% loss on drying, 110 °C
solubility   H2O: soluble0.1 g/mL, clear, colorless (hot)
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤300 mg/kg
cation traces   Ca: ≤30 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤300 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg

Description

Biochem/physiol Actions

Cyanogenic glycoside that is a component of bitter almonds and apricot pits. There is no scientific evidence that amygdalin itself is an effective anti-cancer agent. Recent studies using β−glucoside linked to a tumor-associated monoclonal antibody to release cyanide at the tumor cell has shown significant cytotoxicity.

Other Notes

Review: Cyanogenic glycosides

Application

Amygdalin, a cyanide containing glycoside, may be used as a substrate to identify, differentiate and characterize enzymes such as maltase(s), emulsin(s) and β-glucosidase(s).

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
OO8450000
Protocols & Articles
Peer-Reviewed Papers
15

References

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