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10050 Sigma

Amygdalin

BioXtra, ≥97.0% (HPLC)

Synonym: D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside, D-Mandelonitrile-β-gentiobioside, Laetrile

  • CAS Number 29883-15-6

  • Empirical Formula (Hill Notation) C20H27NO11

  • Molecular Weight 457.43

  •  Beilstein Registry Number 66856

  •  EC Number 249-925-3

  •  MDL number MFCD00006598

  •  PubChem Substance ID 24846528

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C, Cell Biology,
InChI Key   XUCIJNAGGSZNQT-SWRVSKMJSA-N
product line   BioXtra
assay   ≥97.0% (HPLC)
optical activity   [α]20/D −39±2°, c = 2% in H2O
loss   ≤7.5% loss on drying, 110 °C
solubility   H2O: soluble0.1 g/mL, clear to very faintly turbid, colorless (hot)
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤300 mg/kg
cation traces   Ca: ≤30 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤300 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg

Description

Biochem/physiol Actions

Cyanogenic glycoside that is a component of bitter almonds and apricot pits. There is no scientific evidence that amygdalin itself is an effective anti-cancer agent. Recent studies using β−glucoside linked to a tumor-associated monoclonal antibody to release cyanide at the tumor cell has shown significant cytotoxicity.

Other Notes

Review: Cyanogenic glycosides

Application

Amygdalin, a cyanide containing glycoside, may be used as a substrate to identify, differentiate and characterize enzymes such as maltase(s), emulsin(s) and β-glucosidase(s).

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
OO8450000
Protocols & Articles
Peer-Reviewed Papers
15

References

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