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15718 Sigma

D-(+)-Maltose monohydrate

Synonym: 4-O-α-D-Glucopyranosyl-D-glucose, Maltobiose

  • CAS Number 6363-53-7

  • Empirical Formula (Hill Notation) C12H22O11 · H2O

  • Molecular Weight 360.31

  •  Beilstein Registry Number 93798

  •  EC Number 200-716-5

  •  MDL number MFCD00149343

  •  PubChem Substance ID 329750983

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Properties

Related Categories Biochemicals and Reagents, Carbohydrate Chemistry, Carbohydrate Derivatives, Carbohydrates, Carbohydrates A to Z,
InChI Key   HBDJFVFTHLOSDW-DNDLZOGFSA-N
optical activity   [α]20/D +137±2°, c = 10% in H2O (calc.of H2O free subst.)
impurities   ≤0.001% heavy metals (as Pb)
  5-6% water (Karl Fischer)
ign. residue   ≤0.05% (as SO4)
solubility   H2O: soluble180 g/L at 20 °C
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg

Description

Application

D-Maltose has been used for preparing Diamond′s modified TYM medium which is utilized for studying the pharmacodynamic impacts of metronidazole on Trichomonas vaginalis by using time-kill assay. It has also been used as a substrate for the identification, differentiation and characterization of enzymes such as maltase(s); maltose alpha-D-glucosyltransferase(s); maltose-transporting ATPase(s); maltose O-acetyltransferase(s), maltose epimerase(s) and phosphorylase(s). Further, D-Maltose has been used to study maltose-binding proteins and disaccharide transport systems. Other application of D-maltose was in disproportionation activity enzyme assays.

Biochem/physiol Actions

D-Maltose is broken down in the presence of beta-amylases to produce two molecule of glucose followed by glucose metabolism and release of energy. The malP and malQ genes in bacterial genome produce essential enzymes required for maltose metabolism. Beta-amylases are present in plants and bacteria whereas maltase present in humans breaks down the maltose in diet.

Maltose is a disaccharide containing two glucose molecules with an α(1→4) glycosidic linkage. Maltose can be derived from starch in food through the action of amylase. Maltose can be found in many food products, including beer, cereals, and pasta.

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Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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