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17928 Sigma

O-Methyl-O′-succinylpolyethylene glycol 2′000

Synonym: O-(Succinyl)-O′-methylpolyethylene glycol 2′000, Polyethylene glycol 2′000 monomethyl ether succinate

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Properties

Related Categories Biochemicals and Reagents, Carboxylic Acid, Materials Science, Monofunctional PEGs, Peptide Synthesis,
mol wt   Mr ~2100
mp   50-53 °C
Ω-end   COOH
α-end   CH3
storage temp.   −20°C

Description

Packaging

5 g in poly bottle

Application

Polyethylene glycol 2000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.

Biochem/physiol Actions

O-Methyl-O′-succinylpolyethylene glycol 2′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.

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Laboratory Gloves

The Future of Bioimaging
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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