• USA Home
  • 17944 - 1α,25-Dihydroxyvitamin D2

EMAIL THIS PAGE TO A FRIEND
17944 Sigma

1α,25-Dihydroxyvitamin D2

≥97.0% (sum of vitamin and previtamin, HPLC)

Synonym: 1α,25-Dihydroxycalciferol

  • CAS Number 60133-18-8

  • Empirical Formula (Hill Notation) C28H44O3

  • Molecular Weight 428.65

  •  Beilstein Registry Number 5635017

  •  MDL number MFCD00869499

  •  PubChem Substance ID 24850813

Purchase

Properties

Related Categories Cell Biology, Metabolic Pathways, Metabolomics, Nutrition Research, Steroid Metabolism,
InChI Key   ZGLHBRQAEXKACO-XJRQOBMKSA-N
assay   ≥97.0% (sum of vitamin and previtamin, HPLC)
storage temp.   −70°C

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Biochem/physiol Actions

Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol. Activated Vitamin D2 molecules may be used in a wide range of studies to assess their effects on functions such as immune function and calcium homeostasis.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 17944.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Vitamin D and Prevention of Human Disease

Vitamin D2 (ergocalciferol) is naturally synthesized from ergosterol by invertebrates, fungi, and plants in response to ultraviolet B irradiation, while vitamin D3 synthesis (cholecalciferol) is uniq...
Chloe McClanahan
BioFiles 2009, 4.6, 4.
Keywords: Absorption, Angiogenesis, Biofiles, Biological processes, Cancer, Clinical, Gene expression, Growth factors, Hormones, Hydroxylations, Ligands, Metabolites, Transcription, Type, Vitamins

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

42579 4-Phenyl-1,2,4-triazoline-3,5-dione, for HPLC derivatization, ≥98.0% (CHN)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?