|Related Categories||Metabolic Pathways, Metabolomics, Nutrition Research, Steroid Metabolism, Vitamin D,|
|assay||≥97.0% (sum of vitamin and previtamin, HPLC)|
Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 17944.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
|Precautionary statements||P261-P280-P301 + P310-P311|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||63-23/24/25|
|Safety Statements (Europe)||36/37-45|
|RIDADR||UN 2811 6.1/PG 2|
Vitamin D2 (ergocalciferol) is naturally synthesized from ergosterol by invertebrates, fungi, and plants in response to ultraviolet B irradiation, while vitamin D3 synthesis (cholecalciferol) is uniq...
BioFiles 2009, 4.6, 4.
Keywords: Absorption, Angiogenesis, Biological processes, Cancer, Clinical, Gene expression, Growth factors, Hormones, Hydroxylations, Ligands, Metabolites, Transcription, Vitamins
Paricalcitol (19-nor-1,25-dihydroxyvitamin D2) and calcitriol (1,25-dihydroxyvitamin D3) exert potent immunomodulatory effects on dendritic cells and inhibit induction of antigen-specific T cells. Sochorová K, Budinský V, Rozková D, et al. Clin. Immunol. 133, 69-77, (2009)
Micronutrients at the interface between inflammation and infection--ascorbic acid and calciferol: part 1, general overview with a focus on ascorbic acid. Ströhle A, Wolters M, Hahn A. Inflamm. Allergy Drug Targets 10, 54-63, (2011)
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