|Related Categories||Cell Biology, Metabolic Pathways, Metabolomics, Nutrition Research, Steroid Metabolism,|
Synthetic vitamin D3 analog that is metabolized to 1,25-dihydroxycholecalcif
Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol is a synthetic analog that is metabolized to 1,25-dihydroxycholecalcif
Bottomless glass bottle. Contents are inside inserted fused cone.
|Precautionary statements||P260-P264-P280-P284-P302 + P350-P310|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T+|
|Risk Statements (Europe)||26/27/28|
|Safety Statements (Europe)||28-36/37-45|
|RIDADR||UN 2811PIH 6.1 / PGI|
1. Alfacalcidol inhibits bone resorption and stimulates formation in an ovariectomized rat model of osteoporosis: distinct actions from estrogen. Shiraishi, A., et al. J. Bone Miner Res. 15, 770-9, (2000)
Effects of alendronate plus alfacalcidol in osteoporosis patients with a high risk of fracture: the Japanese Osteoporosis Intervention Trial (JOINT) - 02. Orimo H, Nakamura T, Fukunaga M, et al. Curr. Med. Res. Opin. 27(6), 1273-84, (2011)
Alfacalcidol treatment restores derailed immune-regulation in patients with undifferentiated connective tissue disease. Zold E, Szodoray P, Nakken B, Barath S, et al. Autoimmun. Rev. 10, 155-162, (2011)
Vitamin d receptor activators and clinical outcomes in chronic kidney disease. Gravellone L, Rizzo MA, Martina V, et al. Int. J. Nephrol., (2011)
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