|Related Categories||Asymmetric Synthesis, Carboxylic Acid Salts, Cell Biology, Chemical Synthesis, Chiral Building Blocks,|
|optical activity||[α]20/D +27±2°, c = 5% in H2O|
|impurities||≤0.002% heavy metals|
|loss||≤3% loss on drying|
|pH||6.8-7.2 (25 °C, 50 mg/mL in H2O)|
|solubility||H2O: soluble50 mg/mL at 25 °C, clear, almost colorless|
Precursor in the biosynthesis of coenzyme A.
D-Panthenol is the alcohol analogue and biological precursor of D-pantothenic acid. These analogues are precursors in the biosynthesis of coenzyme A. D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation. D-Panthenol may be used for studies of skin protection emulsions from UV irradiation and as a humectant.
Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.
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meets USP testing specifications, monograph mol wt. 476.53 (C18H32CaN2O10)
BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture
Xenobiotics in vitro: the influence of L-cystine, pantothenat, and miliacin on metabolic and proliferative capacity of keratinocytes. Obrigkeit DH, Oepen T, Jugert FK, et al. Cutan. Ocul. Toxicol. 25, 13-22, (2006)
Photoprotective potential of emulsions formulated with Buriti oil (Mauritia flexuosa) against UV irradiation on keratinocytes and fibroblasts cell lines. Zanatta CF, Mitjans M, Urgatondo V, et al. Food Chem. Toxicol. 48, 70-75, (2010)
The effect of pantothenic acid deficiency on keratinocyte proliferation and the synthesis of keratinocyte growth factor and collagen in fibroblasts. Kobayashi D, Kusama M, Onda M, et al. J. Pharmacol. Sci. 115, 230-234, (2011)
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