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21877 Sigma

5(6)-Carboxyfluorescein

BioReagent, suitable for fluorescence, ≥95% (HPLC)

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains,
InChI Key   BPVHBBXCESDRKW-UHFFFAOYSA-N
product line   BioReagent
assay   ≥95% (HPLC)
mp   275 °C (dec.)(lit.)
fluorescence   λex 492 nm; λem 517 nm in 0.1 M Tris pH 8.0
suitability   suitable for fluorescence

Description

Other Notes

A probe of intracellular pH

Application

5(6)-Carboxyfluorescein, fluorescent polyanionic probe, and its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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