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21882 Sigma

5(6)-Carboxy-2′,7′-dichlorofluorescein

BioReagent, suitable for fluorescence, ≥95% (TLC)

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains,
InChI Key   WHFHRELKGQJJBQ-UHFFFAOYSA-N
product line   BioReagent
assay   ≥95% (TLC)
pKa    5.1
mp   ≥250 °C(lit.)
solubility   DMF: soluble
  DMSO: soluble
  H2O: soluble (pH ≥ 5)
fluorescence   λex 504 nm; λem 529 nm in 0.1 M Tris pH 8.0
suitability   suitable for fluorescence

Description

Other Notes

Fluorescent intracellular pH indicator in the pH 4-5 range

Application

5(6)-Carboxy-2′,7′-dichlorofluorescein may be used as a specific substrate/probe to study the identity, activity and specificity of multidrug resistance protein 2 (MRP2) molecules.

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Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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