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  • 21882 - 5(6)-Carboxy-2′,7′-dichlorofluorescein

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21882 Sigma

5(6)-Carboxy-2′,7′-dichlorofluorescein

BioReagent, suitable for fluorescence, ≥95% (TLC)

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains,
InChI Key   WHFHRELKGQJJBQ-UHFFFAOYSA-N
product line   BioReagent
assay   ≥95% (TLC)
pKa    5.1
mp   ≥250 °C(lit.)
solubility   DMF: soluble
  DMSO: soluble
  H2O: soluble (pH ≥ 5)
fluorescence   λex 504 nm; λem 529 nm in 0.1 M Tris pH 8.0
suitability   suitable for fluorescence

Description

Other Notes

Fluorescent intracellular pH indicator in the pH 4-5 range

Application

5(6)-Carboxy-2′,7′-dichlorofluorescein may be used as a specific substrate/probe to study the identity, activity and specificity of multidrug resistance protein 2 (MRP2) molecules.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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