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21884 Sigma

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

BioReagent, suitable for fluorescence, ≥85% (HPCE)

  • CAS Number 127770-45-0

  • Empirical Formula (Hill Notation) C25H14Cl2O9

  • Molecular Weight 529.28

  •  Beilstein Registry Number 7505106

  •  MDL number MFCD08459585

  •  PubChem Substance ID 24853092

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Enzyme Substrates, Fluorescent Enzyme Substrates for Flow Cytometry,
InChI Key   LZMPJBOMBCYYMP-UHFFFAOYSA-N
product line   BioReagent
assay   ≥85% (HPCE)
mp   210 °C (dec.)(lit.)
solubility   DMF: soluble
  DMSO: soluble
  methanol: soluble
fluorescence   λex 470 nm; λem 529 nm in 0.1 M Tris pH 8.0 (esterase)
suitability   suitable for fluorescence
storage temp.   −20°C

Description

Analysis Note

Excmax: 504 nm (Lit.)

Other Notes

Intracellular esterase substrate with low sensitivity of fluorescence to intracellar pH

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate (CDCF) is used as a fluorescent substrate/probe to study the distribution and mechanism of action of multidrug resistance-associated protein 2 (Mrp2).

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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