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21906 Sigma

Carboxymethyl-β-cyclodextrin sodium salt

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Biochemicals and Reagents, Capillary Electrophoresis, Carbohydrates,
InChI Key   WROHVVIPQXODQM-LYSKQWNXSA-N
impurities   10% water
mp   ~245 °C (dec.)
solubility   H2O: soluble50 mg/mL, clear, colorless

Description

Analysis Note

average degree of substitution, DS ~3

Application

Cyclodextrins (CD) are cyclic oligosaccharides composed of D-glucose units connected via α(1→4) glycosidic bonds. Common cyclodextrins contain six (α-CD); seven (β-CD) or eight (gamma-CD) D-glucose units. Cyclodextrins are sometimes derivitized through esterification at positions two, three and/or six.
Carboxymethyl-β-cyclodextrin (CMBCD) is used in the development of recognition and separation technologies to resolve enantiomers based on chiral properties and size. Carboxymethyl-β-cyclodextrin is used in chiral selection and separation by capillary electrophoresis. Carboxymethyl-β-cyclodextrin is used in the development of drug delivery vehicles such as nanocarriers and as a nucleic acid transfection agent.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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