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22244 Sigma

Ceramide from bovine spinal cord

≥98.0% (TLC)

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Ceramides, Lipids, Metabolic Pathways,
assay   ≥98.0% (TLC)
impurities   α-hydroxy fatty acids
solubility   chloroform/methanol (99:1): soluble20 mg/mL, clear, colorless
shipped in   wet ice
storage temp.   −20°C

Description

Other Notes

Sales restrictions may apply

Preparation Note

from cerebrosides by a modification of the procedure by H.E. Carter et al., J. Lipid Res. 2, 228 (1961)

Application

Ceramide is used to investigate effects on programmed cell death (apoptosis) and insulin signaling.

Biochem/physiol Actions

Ceramide is a minor component of cell membranes. Activates atypical protein kinase C (e.g., PKCzeta) .

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Mitochondrial Stress and ROS

Oxidative stress is implicated in the pathogenesis of lipotoxicity in both animal and human studies. Chronic oxidative stress is linked to insulin resistance in multiple tissues. Oxidative stress is ...
BioFiles 2011, 6.4, 22.
Keywords: Anti-inflammatory agents, Apoptosis, Cancer, Cell signaling, Cellular processes, Gene expression, Indicators, Metabolism, Oxidations, Respiratory

Peer-Reviewed Papers
15

References

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