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22620 Sigma

Quinine

suitable for fluorescence, anhydrous, ≥98.0% (dried material, NT)

  • CAS Number 130-95-0

  • Empirical Formula (Hill Notation) C20H24N2O2

  • Molecular Weight 324.42

  •  Beilstein Registry Number 91867

  •  EC Number 205-003-2

  •  MDL number MFCD00198096

  •  PubChem Substance ID 57647993

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Properties

Related Categories Alkaloid, Asymmetric Synthesis, Biochemicals and Reagents, Cell Biology, Chemical Synthesis,
InChI Key   LOUPRKONTZGTKE-WZBLMQSHSA-N
assay   ≥98.0% (dried material, NT)
optical activity   [α]20/D −126±5°, c = 1% in chloroform
impurities   ≤5% dihydroquinine (HPLC)
loss   ≤1% loss on drying, 110 °C
mp   173-175 °C(lit.)
solubility   H2O: soluble
fluorescence   λex 347 nm; λem 448 nm in 0.5 M sulfuric acid
suitability   suitable for fluorescence
Gene Information   human ... ABCB1(5243), CYP2C9(1559), CYP2D6(1565)
rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)

Description

Biochem/physiol Actions

Potassium channel blocker

Other Notes

Chiral catalyst, used e.g. in highly enantioselective [2+2] cycloadditions; In additions of diethylzinc to aldehydes.

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
VA6020000
Protocols & Articles

Articles

HPLC Analysis of Alkaloids on Discovery® RP-AmideC16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Alkaloids on Discovery® RP-AmideC16
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From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Alkaloids on Discovery® Zr-PBD
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Amides on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Amides on Discovery® RP-Amide C16
Keywords: Analgesics, Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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