Synonym: Chrysophanic acid
CAS Number 481-74-3
Empirical Formula (Hill Notation) C15H10O4
Molecular Weight 254.24
Beilstein Registry Number 1252300
EC Number 207-572-2
MDL number MFCD00001208
PubChem Substance ID 24853726
Popular Documents: Specification Sheet (PDF)
| Related Categories | Aloe Vera, Bioactive Small Molecules, Building Blocks, C15 to C38, Carbonyl Compounds, |
| assay | 98% |
| Gene Information | human ... ELA2(1991) |
1 g in glass bottle
50 mg in glass bottle
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.
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