2-Bromohexadecanoic acid
~97%
DOWNLOAD MSDS (PDF)Synonym: 2-Bromopalmitic acid
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CAS Number 18263-25-7
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Linear Formula CH3(CH2)13CH(Br)CO2H
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Molecular Weight 335.32
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Beilstein Registry Number 1726517
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EC Number 242-137-0
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MDL number MFCD00004215
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PubChem Substance ID 24854303
Properties
| Related Categories | B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, |
| assay | ~97% |
| Gene Information | human ... PPARD(5467) |
Description
Packaging
10, 50 g in poly bottle
Biochem/physiol Actions
2-Bromohexadecanoic acid is a PPARδ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation1, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS2.
General description
PPARδ (peroxisome proliferator-activated receptor, delta isoform) acts as a transcription factor for gene expression as well as playing a role in lipid metabolism regulation; activity of this receptor is ligand-regulated. 2-Bromohexadecanoic acid is a metabolically stable analoge of the fatty acid palmitic acid that has been shown to be a natural ligand for the PPARδ receptor.3 2-Bromohexadecanoic acid has also been used in studies of fatty acid oxidation, palmitoylation, and glucose uptake.
Price and Availability
Suggested Laboratory Gloves
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