• USA Home
  • 26430 - Chlortetracycline hydrochloride

EMAIL THIS PAGE TO A FRIEND
26430 Sigma

Chlortetracycline hydrochloride

BioReagent, suitable for fluorescence, from Streptomyces aureofaciens, ≥97.0% (AT)

Synonym: 7-Chlorotetracycline hydrochloride

Purchase

Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,
biological source   from Streptomyces aureofaciens
InChI Key   CBHYYLPALVVVEY-LYNLVHCPSA-N
product line   BioReagent
assay   ≥97.0% (AT)
impurities   ≤3% water
mp   210-215 °C (dec.)(lit.)
solubility   H2O: soluble50 mg/mL
fluorescence   λex 392 nm; λem 536 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+
suitability   suitable for fluorescence
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   −20°C

Description

Application

Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.

Biochem/physiol Actions

Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.
Mode of Resistance: Loss of cell wall permeability.

Quality

Recommended for fluorescent studies of calcium signaling in cells or tissues.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
QI7800000
Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?