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28605 Sigma

3-Cyanoumbelliferone

BioReagent, suitable for fluorescence, ≥98.0% (TLC)

Synonym: 3-Cyano-7-hydroxycoumarin

  • CAS Number 19088-73-4

  • Empirical Formula (Hill Notation) C10H5NO3

  • Molecular Weight 187.15

  •  Beilstein Registry Number 153271

  •  MDL number MFCD00037480

  •  PubChem Substance ID 57648313

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains, pH Indicators for Spectroscopy,
InChI Key   IJQYTHQDUDCJEQ-UHFFFAOYSA-N
product line   BioReagent
assay   ≥98.0% (TLC)
mp   ≥250 °C(lit.)
solubility   DMF: soluble
  alcohols: soluble
fluorescence   λex 408 nm; λem 450 nm in methanol
suitability   suitable for fluorescence
Gene Information   human ... MIF(4282)

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

3-Cyano-7-hydroxycoumarin is closely related to 3-cyano-7-ethoxycoumarin which is used as a fluorometric substrate and inhibitor for cytochrome P-450 enzymes and cytochrome P-450-dependent mixed function oxidases. 3-Cyano-7-hydroxycoumarin may be useful to study the kinetics and substrate specificity of cytochrome P-450s.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

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