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30450 Sigma

Daunorubicin hydrochloride

≥90% (HPLC)

Synonym: Daunomycin hydrochloride

  • CAS Number 23541-50-6

  • Empirical Formula (Hill Notation) C27H29NO10 · HCl

  • Molecular Weight 563.98

  •  Beilstein Registry Number 4229221

  •  EC Number 245-723-4

  •  MDL number MFCD04974507

  •  PubChem Substance ID 24858374

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Description

Biochem/physiol Actions

Potent anticancer agent. Inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent.

On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Daunomycin effectively binds to every 3 base pairs which causes unwinding.

Application

Daunorubicin hydrochloride is used in photostability, antileukemic, and drug metabolism studies.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
HB7878000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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