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30830 Sigma

Dehydrocholic acid

≥99.0% (T)

Synonym: (5β)-3,7,12-Trioxocholan-24-oic acid, 3,7,12-Trioxo-5β-cholanic acid, 5β-Cholanic acid-3,5,12-trione

  • CAS Number 81-23-2

  • Empirical Formula (Hill Notation) C24H34O5

  • Molecular Weight 402.52

  •  Beilstein Registry Number 3226734

  •  EC Number 201-335-7

  •  MDL number MFCD00066410

  •  PubChem Substance ID 57648489

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Properties

Related Categories Anionic Detergents, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents, Detergents,
description   anionic
InChI Key   OHXPGWPVLFPUSM-KLRNGDHRSA-N
assay   ≥99.0% (T)
optical activity   [α]20/D +26±1°, c = 1% in ethanol
mp   238-240 °C
solubility   ethanol: soluble10 mg/mL, clear (hot)

Description

Other Notes

In the production of chenodeoxycholic acid by bioconversion

Preparation Note

Dehydrocholic acid yields clear solution in hot ethanol at 10 mg/ml.

Application

Dehydrocholic acid was used to study the interaction of bile salts with copper ions in unbuffered systems.

Biochem/physiol Actions

Dehydrocholic acid is an oxidation product of cholic acid by chromic acid that is not present in physiological conditions. When used in animal experiments, it stimulates bile secretion.

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Laboratory Gloves

The Future of Bioimaging
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
FZ2300000

Documents

Certificate of Analysis

Protocols & Articles

Articles

HPLC Analysis of Bile Acids on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bile Acids on Ascentis® Express C18
Keywords: Chromatography, Clinical, High performance liquid chromatography

Peer-Reviewed Papers
15

References

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