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31404 Sigma

Dextran sulfate sodium salt from Leuconostoc spp.

Mr 5,000

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Dextran Sulfates for General Research Applications, Dextrans
form   powder
mol wt   Mr 5,000
composition   Sulfur Content, 16.0-20.0%
loss   ≤10% loss on drying
solubility   H2O: soluble0.1 g/mL, clear, colorless to slightly yellow
  H2O: freely soluble50 mg/mL, clear

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Preparation Note

prepared from dextran with Mr ~5000

Application

Dextran sulfate sodium salt from Leuconostoc sp. is a polyanion used as a test reagent for testing its capability to rupture the extracellular enveloped virus (EEV) outer membrane. It has also been used for assessing the impact of TLR4 monoclonal antibody on the growth of dextran-sulfate-sodium-(DSS)-induced colitis.

Biochem/physiol Actions

Dextran is a mixture of glucose polymers of varying size and geometry.Dextran in the form of dextran sulphate sodium acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength. The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
HH9290000

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
What does Mr refer to on the website product page for Product 31404, Dextran sulfate sodium salt from Leuconostoc spp.?
Mr stands for relative molecular weight, which is the molecular weight calculated by atomic mass.
Do you have information regarding possible applications for Product No. 31404, Dextran sulfate sodium salt from Leuconostoc spp.?
Please see our product data sheet, which lists several product applications: http://www.sigmaaldrich.com/etc/medialib/docs/Fluka/Datasheet/31404dat.Par.0001.File.tmp/31404dat.pdf
What is the composition of Product No. 31404, Dextran sulfate sodium salt from Leuconostoc spp.?
Please see our product data sheet, which has a detailed product description: http://www.sigmaaldrich.com/fluka/product%20information%20sheet/31404_31396_128kb.pdf
How should Dextran sulfate sodium salt from Leuconostoc spp., Product 31404, be stored?
We would recommend storing this product at room temperature, which is in accordance with our MSDS.
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
Show more questions
Protocols & Articles

Articles

Dextran and Related Polysaccharides

Historically, dextrans had been long recognized as contaminants in sugar processing and other food production. The formation of dextran in wine was shown by Pasteur to be due to the activity of micro...
Vicki Caligur
BioFiles 2008, 3.10, 17.
Keywords: Adhesion, Applications, Chromatography, Clinical, Cosmetics, Derivatizations, Diffusion, Filtration, Immobilization, Industries, Ion Exchange, Ligands, Microscopy, Molecular biology, Molecular biology techniques, Nuclear magnetic resonance spectroscopy, Nucleic acid hybridization, Pharmaceutical, Precipitation, Purification, Separation, Size-exclusion chromatography, Spectroscopy, Sulfations, Type

FITC-labelled polysaccharides

FITC-Dextran FITC-DEAE-dextran (FDD) FITC-carboxymethyl-dextran (FCM-Dextran) FITC-polysucrose (FITC-Ficoll®) FITC-DEAE-polysucrose FITC-CM-polysucrose (FITC-CM-Ficoll®) FITC-inulin Fluorescein hyalu...
Keywords: Absorption, Amidations, Bacterial conjugations, Cosmetics, Diabetes, Diagnostic, Esterifications, Filtration, Microscopy, Pharmaceutical, Separation, Size-exclusion chromatography, Solvents, Substitutions, Transfection

Peer-Reviewed Papers
15

References

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