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36105 Sigma

(±)-Sodium β-hydroxyisobutyrate

≥96.0%

Synonym: β-Hydroxyisobutyric acid sodium salt, (±)-β-HIBA-Na, 3-Hydroxy-2-methylpropionic acid sodium salt, Sodium 3-hydroxy-2-methylpropionate

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Properties

Related Categories Cancer Metabolism, Cancer Research, Cell Biology, Fatty Acid Metabolism in Oncogenesis, Gluconeogenesis,
InChI Key   RBJZIQZDAZLXEK-UHFFFAOYSA-M
assay   ≥96.0% (GC)
  ≥96.0%
composition   sodium, 17.5-19.0%
storage temp.   2-8°C

Description

Biochem/physiol Actions

3-Hydroxyisobutyrate (HIBA), is formed in the valine catabolism, it is a reactant of enzyme 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4); it was found to have increased concentrations in MS patient metabolic profiles.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4).

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All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

New Metabolomics Products

The availability of metabolites is an important element for progress in metabolomics. We have expanded our collection in an effort to provide you with the metabolites needed to advance your research.
Keywords: Metabolites, Metabolomics

Peer-Reviewed Papers
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References

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