|Related Categories||Antibiotics, Antiviral, Biochemicals and Reagents, Cell Biology, Nutrition Research,|
|optical activity||[α]20/D +76°, c = 0.5 in methanol|
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100 mg in glass bottle
Artemisinin (Qinghaosu), a sesquiterpene lactone, is a highly active anti-malarial (falciparum malaria) drug. Artemisinin is also an anthelmintic (parasitic worm) effective against the blood fluke, schistosomiasis.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 361593.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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C2-symmetrical, chiral 2,2’-bipyrrolidines have recently emerged as interesting structural chiral motifs in a number of ligands for asymmetric transformations (Figure 1). When the two nitrogen atoms ...
ChemFiles Volume 10 Article 4
Keywords: Asymmetric synthesis, Catalysis, Dihydroxylations, Ligands, Oxidations, Preferential Oxidation
Traditional Chinese Medicine (TCM) is a healing art that has been practiced for thousands of years. The practice of TCM is a holistic approach that includes the use of herbal preparations, acupunctur...
Lynn Stephenson, Product Specialist, Sigma® Life Science and Chloe McClanahan, Product Manager, Sigma Life Science
Biofiles Vol. 8, No. 6
Keywords: Analgesics, Antitumor agents, Apoptosis, Cancer, Drug discovery, Fractionation, High performance liquid chromatography, Metabolites, Metabolomics, Nuclear magnetic resonance spectroscopy, Pharmaceutical
Schistosoma mansoni: N-acetylcysteine downregulates oxidative stress and enhances the antischistosomal activity of artemether in mice. Seif el-Din SH, Al-Hroob AM, Ebeid FA. Exp. Parasitol. 128, 230-235, (2011)
Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Li JX, Fang X, Zhao Q, et al. Biochem. J. 451(3), 417-26, (2013)
Synthesis and antimalarial efficacy of two-carbon-linked, artemisinin-derived trioxane dimers in combination with known antimalarial drugs. Mott BT, Tripathi A, Siegler MA, et al. J. Med. Chem. 56(6), 2630-41, (2013)
Bioassay of Artemisia annua leaf extracts and artemisinin against larvae of Culex quinquefasciatus and Culex tritaeniorhynchus. Sharma G, Kumar K, Sharma A, et al. J. Am. Mosq. Control Assoc. 28(4), 317-9, (2012)
In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains. Abiodun OO, Brun R, and Wittlin S Malaria Journal 12, 43, (2013)
Understanding the impact of subsidizing artemisinin-based combination therapies (ACTs) in the retail sector--results from focus group discussions in rural Kenya. Kedenge SV, Kangwana BP, Waweru EW, et al. PLoS ONE 8(1), e54371, (2013)
The effect of an anti-malarial subsidy programme on the quality of service provision of artemisinin-based combination therapy in Kenya: a cluster-randomized, controlled trial. Kangwana BP, Kedenge SV, Noor AM, et al. Malaria Journal 12, 81, (2013)
Mutation analysis in pfmdr1 and pfmrp1 as potential candidate genes for artemisinin resistance in Plasmodium falciparum clinical isolates 4years after implementation of artemisinin combination therapy in Iran. Pirahmadi S, Zakeri S, Afsharpad M, et al. Infect. Genet. Evol. 14, 327-34, (2013)
Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda. Jagannathan P, Muhindo MK, Kakuru A, et al. Malaria Journal 11, 435, (2012)
FT-IR 2 (1), 1200:B / FT-NMR 1 (1), 1163:B / RegBook 1 (1), 819:K / Structure Index 1, 128:C:8
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