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39220 Sigma

Dansyl chloride

BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

Synonym: 5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl

  • CAS Number 605-65-2

  • Empirical Formula (Hill Notation) C12H12ClNO2S

  • Molecular Weight 269.75

  •  Beilstein Registry Number 2217205

  •  EC Number 210-092-6

  •  MDL number MFCD00003985

  •  PubChem Substance ID 329755828

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Properties

Related Categories Alphabetical, Amino Acid Analysis, Amino Acids, Analytical Reagents, Analytical/Chromatography,
InChI Key   XPDXVDYUQZHFPV-UHFFFAOYSA-N
product line   BioReagent
assay   ≥99.0% (HPLC)
mp   72-74 °C(lit.)
solubility   acetone: soluble0.2 g/10 mL
fluorescence   λex 337 nm; λem 492 nm in chloroform (after derivatization with hexylamine)
suitability   suitable for fluorescence
storage temp.   2-8°C

Description

Application

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

Dansyl chloride (DNSC), a primary amine reactive agent, is widely used as a fluorogenic reagent for N-terminal derivatization of amino acids and peptides and for polyamine detection by reverse phase HPLC and other analytical procedures.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
3
RTECS 
QK3688000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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