• USA Home
  • 40227 - 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine

40227 Sigma


suitable for fluorescence, ≥97.0% (HPLC)

Synonym: 2-(Dimethylamino)-6-dodecanoylnaphthalene, Laurdan, N,N-Dimethyl-6-dodecanoyl-2-naphthylamine

  • CAS Number 74515-25-6

  • Empirical Formula (Hill Notation) C24H35NO

  • Molecular Weight 353.54

  •  Beilstein Registry Number 7379104

  •  MDL number MFCD00467560

  •  PubChem Substance ID 57649941



Related Categories Alphabetical, Biochemicals and Reagents, Detection, Environmental Sensitive Membrane Probes, Fluorescent Indicators and Probes,
assay   ≥97.0% (HPLC)
mp   88 °C(lit.)
solubility   DMF: soluble
  acetonitrile: soluble
  methanol: soluble
fluorescence   λex 366 nm; λem 497 nm in methanol
suitability   suitable for fluorescence


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Other Notes

Fluorescent membrane probe


Bottomless glass bottle. Contents are inside inserted fused cone.


6-Dodecanoyl-N,N-dimethyl-2-naphthylamine (Laurdan) is a fluorescent probe used to study membrane structure, order and dynamic processes such as fluidity.

Price and Availability

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
What is the appearance of Product No. 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?
Product 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine) is described as powder to fine flakes.
What is the solubility of Product No. 40227(6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?
Product 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine) is soluble in N,N-dimethylformamide (DMF), methanol and acetonitrile.  It is also reported to be soluble in chloroform, according to Journal of Biological Chemistry, 248, 40186-40197 (2003). Here is the link to that paper: http://www.jbc.org/content/278/41/40186.full.   
What are some of the physical properties of Product No. 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?
The physical properties of  6-Dodecanoyl-N,N-dimethyl-2-naphthylamine are: Boiling Point: 497.4 ºC at atmospheric pressure (760 mm Hg) Flash Point: 177.4 ºC Melting Point: 88ºC(lit.) Density: 0.987 g/cm3 Vapor Pressure: 4.95-10 mm Hg at 25°C Refractive Index: 1.553
What are the spectral properties (excitation and emission maxima) of 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, Laurdan, Product 40227?
The spectral properties of 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine are: λex 366 nm; λem 497 nm in methanol.
Show more questions
Protocols & Articles


Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?