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42867 Sigma

Dextran sulfate sodium salt

Mr ~40,000

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Dextran Sulfates for General Research Applications, Dextrans
mol wt   Mr ~40,000
loss   ≤10% loss on drying
solubility   water: soluble
storage temp.   room temp

Description

Application

Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Biochem/physiol Actions

Treatment with dextran sulfate sodium triggers development of colitis in mice and rats by binding to medium-chain-length fatty acids present in the colon and inducing inflammation.

General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




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Safety & Documentation

Safety Information

WGK Germany 
2

Documents

Certificate of Analysis

Protocols & Articles

Articles

FITC-labelled polysaccharides

FITC-Dextran FITC-DEAE-dextran (FDD) FITC-carboxymethyl-dextran (FCM-Dextran) FITC-polysucrose (FITC-Ficoll®) FITC-DEAE-polysucrose FITC-CM-polysucrose (FITC-CM-Ficoll®) FITC-inulin Fluorescein hyalu...
Keywords: Absorption, Amidations, Bacterial conjugations, Cosmetics, Diabetes, Diagnostic, Esterifications, Filtration, Microscopy, Pharmaceutical, Separation, Size-exclusion chromatography, Solvents, Substitutions, Transfection

Peer-Reviewed Papers
15

References

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