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42867 Sigma

Dextran sulfate sodium salt

Mr ~40,000

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Dextran Sulfates for General Research Applications, Dextrans
mol wt   Mr ~40,000
loss   ≤10% loss on drying
solubility   water: soluble
storage temp.   room temp

Description

Application

Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Biochem/physiol Actions

Treatment with dextran sulfate sodium triggers development of colitis in mice and rats by binding to medium-chain-length fatty acids present in the colon and inducing inflammation.

General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Protocols & Articles

Articles

FITC-labelled polysaccharides

FITC-Dextran FITC-DEAE-dextran (FDD) FITC-carboxymethyl-dextran (FCM-Dextran) FITC-polysucrose (FITC-Ficoll®) FITC-DEAE-polysucrose FITC-CM-polysucrose (FITC-CM-Ficoll®) FITC-inulin Fluorescein hyalu...
Keywords: Absorption, Amidations, Bacterial conjugations, Cosmetics, Diabetes, Diagnostic, Esterifications, Filtration, Microscopy, Pharmaceutical, Separation, Size-exclusion chromatography, Solvents, Substitutions, Transfection

Peer-Reviewed Papers
15

References

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