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42867 Sigma

Dextran sulfate sodium salt

Mr ~40,000



Related Categories Biochemicals and Reagents, Carbohydrates, Dextran Sulfates for General Research Applications, Dextrans
mol wt   Mr ~40,000
loss   ≤10% loss on drying
solubility   water: soluble
storage temp.   room temp



Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Biochem/physiol Actions

Treatment with dextran sulfate sodium triggers development of colitis in mice and rats by binding to medium-chain-length fatty acids present in the colon and inducing inflammation. 1

General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Price and Availability

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Dextran sulfate sodium salt from <I>Leuconostoc</I> spp.

for molecular biology, average Mw >500,000 (dextran starting material), contains 0.5-2% phosphate buffer

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Safety Information

WGK Germany 


Certificate of Analysis

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