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42965 Sigma

Tramadol hydrochloride

≥99.0% (HPLC)

Synonym: (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride, Tramadol HCl

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Properties

InChI Key   PPKXEPBICJTCRU-XMZRARIVSA-N
assay   ≥99.0% (HPLC)
drug control   USDEA Schedule IV
mp   178-181 °C

Description

Biochem/physiol Actions

Opioid analgesic; P450 substrate.

Tramadol hydrochloride (HCl) inhibits the reuptake of norepinephrine and serotonin in μ-opioid receptors in rat models in vitro.

Application

Tramadol hydrochloride has been used to study the tramadol biosynthesis route in plants.

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Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN2811 - class 6.1 - PG 3 - MP - EHS - Toxic solids, organic, n.o.s., HI: all
WGK Germany 
2
Protocols & Articles

Articles

HPLC Analysis of Tramadol Enantiomers on Astec® CYCLOBOND® I 2000 DMP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tramadol Enantiomers on Astec® CYCLOBOND® I 2000 DMP
Keywords: Analgesics, Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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