• USA Home
  • 43420 - β-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate

EMAIL THIS PAGE TO A FRIEND
43420 Sigma

β-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate

≥97.0% (HPLC)

Synonym: β-DPNH, β-NADH, DPNH, Diphosphopyridine nucleotide, reduced form, NADH

Purchase

Properties

Related Categories Biochemicals and Reagents, Bulk vials, NAD(P)(H) and Analogs, NADH, Nucleosides, Nucleotides, Oligonucleotides More...
InChI Key   FWBNCIFELNNJCX-UHOVGGJYSA-L
assay   ≥97.0% (HPLC)
cation traces   Ca: ≤200 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤20 mg/kg
  Fe: ≤5 mg/kg
  K: ≤200 mg/kg
  Mg: ≤200 mg/kg
  Mn: ≤5 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
absorbance ratio   A260/340 nm ≤2.40
storage temp.   2-8°C

Description

Packaging

Packaged by solid weight.

Application

As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Nicotinamide adenine dinucleotide (NAD) and NADH form a redox pair. NAD/NADH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications. NAD is also involved in post-translational (Poly(ADP-ribose) polymerization) modifications of proteins.

Biochem/physiol Actions

NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, β-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). It participates in cell signaling events as well, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. The NAD+/NADH dependent sirtuins play key roles in stress responses during events involving energy metabolism, with implications in cancer biology, diabetes and neurodegenerative disease.
As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?