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43683 Sigma

Disialoganglioside GD3 from bovine milk

≥90% (TLC), ammonium salt

Synonym: Ganglioside GD3, disialo

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Properties

Related Categories Acidic Glycosphingolipids, Biochemicals and Reagents, Gangliosides, Lipids, Sphingolipids More...
assay   ≥90% (TLC)
storage temp.   −20°C

Description

Other Notes

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Tumor-specific antigen in malignant melanoma. Antibodies to GD3 can induce partial remission of tumor growth in animals and humans

Biochem/physiol Actions

Disialoganglioside GD3 plays an important role in CD95- and ceramide-induced apoptosis in hematopoietic cells as well as TNF-α-induced apoptosis iin hepatocytes and colon cells , thus acting as a cell death effector.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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