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43683 Sigma

Disialoganglioside GD3 from bovine milk

≥90% (TLC), ammonium salt

Synonym: Ganglioside GD3, disialo

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Properties

Related Categories Acidic Glycosphingolipids, Biochemicals and Reagents, Gangliosides, Lipids, Sphingolipids More...
assay   ≥90% (TLC)
storage temp.   −20°C

Description

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Tumor-specific antigen in malignant melanoma. Antibodies to GD3 can induce partial remission of tumor growth in animals and humans

Biochem/physiol Actions

Disialoganglioside GD3 plays an important role in CD95- and ceramide-induced apoptosis in hematopoietic cells as well as TNF-α-induced apoptosis iin hepatocytes and colon cells , thus acting as a cell death effector.

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Laboratory Gloves

The Future of Bioimaging
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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