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43794 Sigma

1,4-Dithioerythritol

BioUltra, ≥99.0% (RT)

Synonym: erythro-1,4-Dimercapto-2,3-butanediol, erythro-2,3-Dihydroxy-1,4-butanedithiol, Cleland’s reagent, DTE

  • CAS Number 6892-68-8

  • Linear Formula HSCH2CH(OH)CH(OH)CH2SH

  • Molecular Weight 154.25

  •  Beilstein Registry Number 1719756

  •  EC Number 229-998-8

  •  MDL number MFCD00063750

  •  PubChem Substance ID 24867409

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Properties

Related Categories Alphabetical, BioUltra, Biochemicals and Reagents, Carbohydrates, Denaturation,
InChI Key   VHJLVAABSRFDPM-ZXZARUISSA-N
product line   BioUltra
assay   ≥99.0% (RT)
impurities   insoluble matter, passes filter test
  ≤0.5% 4,5-dihydroxy-1,2-dithiane
pH   4.0-6.0 (25 °C, 0.1 M in H2O)
mp   82-84 °C(lit.)
  82-85 °C
solubility   H2O: soluble0.1 M at 20 °C, clear, colorless
anion traces   sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.5 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤50 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   0.1 M in H2O
UV absorption   λ: 260 nm Amax: 0.400
  λ: 280 nm Amax: 0.050
storage temp.   2-8°C

Description

Application

Reagent for maintaining −SH groups in the reduced state; quantitatively reduces disulfides.

Other Notes

Cleavage of disulfide bonds in proteins; Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
UN 3335
WGK Germany 
3
RTECS 
KF2410000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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