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45480 Sigma

Ergosterol

≥95.0% (HPLC)

Synonym: 3β-Hydroxy-5,7,22-ergostatriene, 5,7,22-Ergostatrien-3β-ol, Provitamin D2

  • CAS Number 57-87-4

  • Empirical Formula (Hill Notation) C28H44O

  • Molecular Weight 396.65

  •  Beilstein Registry Number 2338604

  •  EC Number 200-352-7

  •  MDL number MFCD00003623

  •  PubChem Substance ID 329756772

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Elettaria Cardamomum (Cardamom), Ginkgo biloba, Metabolic Pathways,
InChI Key   DNVPQKQSNYMLRS-APGDWVJJSA-N
assay   ≥95.0% (HPLC)
optical activity   [α]20/D −120±10°, c = 1% in chloroform
impurities   ~3% water
mp   156-158 °C(lit.)
  160-163 °C
storage temp.   2-8°C

Description

Packaging

10, 50 g in poly bottle

Biochem/physiol Actions

Ergosterol is a biological precursor of Vitamin D2 found in cell membranes of fungi and some protists such as trypanosomes. Ergosterol may be used to study the function of anti-fungal drugs such as Amphotericin B and its analogues and to study the ergosterol biosynthesis pathway within various fungi.

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Vitamin D and Prevention of Human Disease

Vitamin D2 (ergocalciferol) is naturally synthesized from ergosterol by invertebrates, fungi, and plants in response to ultraviolet B irradiation, while vitamin D3 synthesis (cholecalciferol) is uniq...
Chloe McClanahan
BioFiles 2009, 4.6, 4.
Keywords: Absorption, Angiogenesis, Biofiles, Biological processes, Cancer, Clinical, Gene expression, Growth factors, Hormones, Hydroxylations, Ligands, Metabolites, Transcription, Type, Vitamins

Peer-Reviewed Papers
15

References

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