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45703 Sigma

Erythromycin standard solution

1 mg/mL in H2O

  • CAS Number 114-07-8

  • Empirical Formula (Hill Notation) C37H67NO13

  • Molecular Weight 733.93

  •  Beilstein Registry Number 8183758

  •  MDL number MFCD00084654

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Properties

Related Categories 1694 Pharmaceuticals & Personal Care Products, A - K, Additional Standards, Analytical Standards, Analytical/Chromatography,
InChI Key   ULGZDMOVFRHVEP-RWJQBGPGSA-N
concentration   1 mg/mL in H2O
suitability   suitable for 1694 per US EPA
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-positive bacteria
storage temp.   2-8°C

Description

Caution

This Erythromycin solution is concentrated at 1 mg/mL in H2O and is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.

Application

Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains. .

Biochem/physiol Actions

Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex.

Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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