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46946 Sigma

Fluorescein isothiocyanate–dextran

average mol wt 150,000, (FITC:Glucose = 1:160)

Synonym: FITC–Dextran, FITC-Dextran 150

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Conjugates, Fluorescent Conjugates for Flow Cytometry,
assay   (FITC:Glucose = 1:160)
mol wt   average mol wt 150,000
extent of labeling   ~0.004 mol/mol FITC glucose
solubility   H2O: 25 mg/mL, slightly hazy, very deep yellow-orange
fluorescence   λex 492 nm; λem 518 nm in 0.1 M phosphate pH 8.0
storage temp.   2-8°C
  2-8°C

Description

Other Notes

Commonly utilized as a macromolecular fluorochrome in inflammatory studies

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Fluorescein isothiocyanate–dextran (FITC-Dextran 150) is use as a fluorescent probe to study cell permeability. FITC-Dextran 150 is useful to study processes that affect the permeability of the blood brain barrier (BBB) and microvascular structures. FITC-Dextran 150 is used in fluorescence microlymphography.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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