Folinic acid calcium salt hydrate
BioXtra, ≥99.0% (HPLC)
DOWNLOAD MSDS (PDF)Synonym:
5-
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CAS Number 1492-18-8 (anhydrous)
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Empirical Formula (Hill Notation) C20H21CaN7O7 · xH2O
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Molecular Weight 511.50 (anhydrous basis)
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Beilstein Registry Number 5723924
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PubChem Substance ID 24871209
Properties
| Related Categories | Coenzymes and Cofactors, Folic Acid, Folic Acid Metabolism, Metabolic Pathways, Metabolomics, |
| product line | BioXtra |
| assay | ≥99.0% (HPLC) |
Description
Application
Calcium folinate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.
General description
Calcium salt of the (6R,S)-mixture of diastereomers of 5-formyl-5,6,7,8-tetrahyd
Other Notes
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