|Related Categories||Coenzymes and Cofactors, Folic Acid, Folic Acid Metabolism, Metabolic Pathways, Metabolomics,|
Calcium folinate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.
Calcium salt of the (6R,S)-mixture of diastereomers of 5-formyl-5,6,7,8-tetrahyd
|Precautionary statements||P261-P280-P305 + P351 + P338-P342 + P311|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Faceshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||36/37/38-42/43|
|Safety Statements (Europe)||26-36|
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