Synonym: Fura-2 pentakis(acetoxymethyl) ester
|Related Categories||Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Biochemicals and Reagents,|
|fluorescence||λex 355 nm; λem 495 nm in 0.1 M Tris pH 8.0, esterase; 10 mM Ca2+|
|suitability||suitable for fluorescence|
Membrane-permeable derivative of Fura-2. Used to load the chelator into cells. Hydrolysed enzymatically in the cell to yield Fura-2 which remains within the cell1,2,3,4
Fura-2 pentakis(acetoxymethyl) ester (Fura 2/AM), a fluorescence probe, is a membrane-permeable derivative of the calcium chelator Fura-2. Fura 2/AM is used to monitor intracellular levels of calcium under various physiological conditions.
In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
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Green tea catechins increase the force of contraction in isolated Guinea pig atrial muscle preparations by increasing the amplitude of intracellular ca(2+) concentration. Sasaki T, Kamata R, Ueno S, et al. J. Vet. Med. Sci. 74, 1603-1608, (2012)
[Study on Ca2+ transmembrane behaviors of magnetic-treated S. aureus with Fura-2/AM fluorescence probe and LCSM].[Article in Chinese] Ma HL, Xu SS, He RH, Duan YQ. Guang Pu Xue Yu Guang Pu Fen Xi 332, 407-410, (2012)
Intracellular Levels of Na(+) and TTX-sensitive Na (+) Channel Current in Diabetic Rat Ventricular Cardiomyocytes. Bilginoglu A, Kandilci HB, Turan B. Cardiovasc. Toxicol., 138-147, (2012)
Reduced RhoA activity mediates acute alcohol intoxication-induced inhibition of lymphatic myogenic constriction despite increased cytosolic [Ca(2+) ]. Souza-Smith FM, Molina PE, Breslin JW. Microcirculation, (2012)
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