• USA Home
  • 48279 - β-1,4-Galactosyl Transferase from bovine milk

EMAIL THIS PAGE TO A FRIEND
48279 Sigma

β-1,4-Galactosyl Transferase from bovine milk

≥0.6 U/mg

Synonym: Lactose Synthase

Purchase

Description

Other Notes

Galactosyltransferases, physical, chemical and biological aspects

Sales restrictions may apply

Unit Definition

1 U correspond to the amount of enzyme which transfers 1 μmol galactose from UDP-galactose to D-glucose per minute at pH 8.4 and 30°C in the presence of α-lactalbumin

Biochem/physiol Actions

β-1,4-Galactosyl Transferase catalyzes the transfer of galactose from UDP-galactose to the terminal N-acetylglucosamine residues on elongating oligosaccharide chains. It is also considered to be a biosynthetic enzyme of the Golgi apparatus. β-1,4-Galactosyl Transferase can also be found on the cell surface functioning as a cell-adhesion molecule during various cellular interactions by binding to N-acetylglucosamine containing oligosaccharide substrates or ligands in the extracellular matrix.

Price and Availability


Amplified Detection
Safety & Documentation

Safety Information

WGK Germany 
3
Protocols & Articles

Articles

Glycosyltransferases: Tools for Synthesis and Modification of Glycans

The presence of multiple functional groups and stereocenters in complex carbohydrates makes them challenging targets for the organic chemist. Chemical synthesis research has not yielded robust, autom...
BioFiles 2007, 2.1, 2.
Keywords: Acylations, Bacterial conjugations, Biochemistry, Catalysis, Enzyme activity, Fucosylation, Gene expression, Glycosylations, Methods, Organic synthesis, Protocols, Sequences, Solvents, Type

Glycosyltransferases

Glycosyltransferases are specific for the type of linkage (α or β), and the linkage position of the glycoside bond formed [e.g. α(1→3) or β(1→4)]. Glycosyltransferases were initially considered to be...
Glycobiology Analysis Manual, 2nd Edition
Keywords: Catalysis, Cell signaling, Enzyme activity, Glycosylations, Pharmaceutical, Type

β-(1—>4)-Galactosyltransferase Kit

β(1→4) Galactosyltransferase from bovine milk (GalT, EC 2.4.1.22) is one of the most extensively studied mammalian glycosyltransferases with regard to synthesis and substrate specificity.[1-5, 9-15] ...
ChemFiles Volume 3 Article 6
Keywords: Biochemistry, Capabilities, Catalysis, Fucosylation, Glycosylations, Organic synthesis, Solvents

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?