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48760 Sigma

Gentamicin sulfate from Micromonospora purpurea

~700 U/mg dried material

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Properties

Related Categories A - K, Aminoglycosides, Antibacterial, Antibiotics, Antibiotics A to Z,
biological source   from Micromonospora purpurea
material   white to light yellow
InChI Key   RDEIXVOBVLKYNT-HDZPSJEVSA-N
form   powder
optical activity   [α]20/D +110±8°, c = 1% in H2O
shelf life   6 yr
mol wt   Mr 694-723
impurities   ≤10% water
pH   4.0-5.5 (0.1 g/mL in H2O)
mp   218-237 °C
solubility   H2O: soluble0.1 g/mL, clear, very faintly yellow
Mode of action   protein synthesis | interferes
storage temp.   2-8°C

Description

Application

Used as a selection agent (gentamicin-resistance gene) in molecular biology applications.

Biochem/physiol Actions

Mode of Action: Inhibits protein synthesis by binding to L6 protein of 50S ribosomal subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.

Unit Definition

1 U corresponds to 1 μg of the USP gentamicin sulfate reference standard

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
LY2625000
Protocols & Articles
Peer-Reviewed Papers
15

References

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