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49449 Sigma

L-Glutamic acid

BioUltra, ≥99.5% (NT)

Synonym: (S)-2-Aminopentanedioic acid, Glu

  • CAS Number 56-86-0

  • Linear Formula HO2CCH2CH2CH(NH2)CO2H

  • Molecular Weight 147.13

  •  Beilstein Registry Number 1723801

  •  EC Number 200-293-7

  •  MDL number MFCD00002634

  •  PubChem Substance ID 57651195

  •  eCl@ss 32160406

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Properties

Related Categories Amino Acids, BioUltra, Biochemicals and Reagents, Proteins and Amino Acids for Protein Stabilization, Proteins and Derivatives,
InChI Key   WHUUTDBJXJRKMK-VKHMYHEASA-N
product line   BioUltra
assay   ≥99.5% (NT)
optical activity   [α]20/D +31.5±1.0°, c = 5% in 5 M HCl
impurities   insoluble matter, passes filter test
  ≤0.5% foreign amino acids
ign. residue   ≤0.05% (as SO4)
loss   ≤0.05% loss on drying, 20 °C (HV)
mp   205 °C (dec.)(lit.)
solubility   1 M HCl: 1 M at 20 °C clear, colorless
anion traces   chloride (Cl-): ≤100 mg/kg
  sulfate (SO42-): ≤200 mg/kg
cation traces   Al: ≤5 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤200 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  NH4+: ≤100 mg/kg
  Na: ≤200 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in 1 M HCl
UV absorption   λ: 260 nm Amax: 0.1
  λ: 280 nm Amax: 0.1
Gene Information   human ... CCR2(1231), GRIA1(2890), GRIA2(2891), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK5(2901), GRIN2B(2904), GRM2(2912), SLC1A1(6505), SLC1A2(6506)
rat ... Gria1(50592), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409), Grm1(24414), Grm2(24415), Grm3(24416), Grm4(24417), Grm5(24418), Grm6(24419), Grm7(81672), Slc1a2(29482)

Description

Biochem/physiol Actions

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Other Notes

Lesion-sparing agent, has excitotoxic properties; May function as precipitating agent in protein crystallization; Growth requirement of various microorganisms

Price and Availability


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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Protocols & Articles

Related Content

Amino Acids Reference Chart

The hydrophobicity index is a measure of the relative hydrophobicity, or how soluble an amino acid is in water. In a protein, hydrophobic amino acids are likely to be found in the interior, whereas h...

Peer-Reviewed Papers
15

References

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