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50649 Sigma

Glyoxal solution

BioReagent, for molecular biology, ~40% in H2O (~8.8 M)

Synonym: Ethanedial, Oxalaldehyde

  • CAS Number 107-22-2

  • Linear Formula OHCCHO

  • Molecular Weight 58.04

  •  Beilstein Registry Number 1732463

  •  MDL number MFCD00006957

  •  PubChem Substance ID 57651264

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Properties

Related Categories Aldehydes, Building Blocks, C1 to C6, Carbonyl Compounds, Chemical Synthesis,
grade   for molecular biology
InChI Key   LEQAOMBKQFMDFZ-UHFFFAOYSA-N
product line   BioReagent
form   liquid
concentration   ~40% in H2O (~8.8 M)
impurities   DNases, none detected
  RNases, none detected
  phosphatases, none detected
  proteases, none detected
refractive index   n20/D 1.409
anion traces   chloride (Cl-): ≤100 mg/kg
  sulfate (SO42-): ≤100 mg/kg
cation traces   Ca: ≤5 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤300 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
storage temp.   2-8°C

Description

Caution

May precipitate on storage; redissolve at 50-60 °C.

Other Notes

This form of glyoxal is composed of 3 moles of glyoxal and 2 moles of water in a relatively stable configuration.

May precipitate on storage; redissolve at 50-60 °C.

Principle

Glyoxal forms stable complex with guanine residues that results in denaturation of nucleic acids.

Application

Suitable for
• nucleic acid denaturation
• binding of DNA/RNA to nitrocellulose membrane

General description

Glyoxal is a nucleic acid denaturant. It acts as a specific probe for homopurine strands of DNA.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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