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50950 Sigma

Guanidine hydrochloride

≥98%

Synonym: Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride

  • CAS Number 50-01-1

  • Linear Formula NH2C(=NH)NH2 · HCl

  • Molecular Weight 95.53

  •  Beilstein Registry Number 3591990

  •  EC Number 200-002-3

  •  MDL number MFCD00013026

  •  PubChem Substance ID 57651288

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Properties

Related Categories Biochemicals and Reagents, Chaotropic Agents, Core Bioreagents, Denaturation, Nucleosides and Nucleotides,
InChI Key   PJJJBBJSCAKJQF-UHFFFAOYSA-N
assay   ≥98%
pH   (25 °C, 4.6 - 6/573 g/L)
mp   180-185 °C(lit.)
solubility   H2O: soluble6 M, clear (100 Hazen)

Description

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Packaging

1, 2.5 kg in poly bottle

250 g in poly bottle

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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