51280 Sigma


BioXtra, from Porcine, ≥97.0% (HPLC)

Synonym: Chloro(protoporphyrinato)iron(III), Chlorohemin, Chloroprotoporphyrin IX iron(III), Ferriprotoporphyrin IX chloride, Hemin(chloride)

  • CAS Number 16009-13-5

  • Empirical Formula (Hill Notation) C34H32ClFeN4O4

  • Molecular Weight 651.94

  •  Beilstein Registry Number 5229914

  •  EC Number 240-140-1

  •  MDL number MFCD00010726

  •  PubChem Substance ID 57651319



Frequently Asked Questions

Frequently Asked Questions are available for this Product.


Hemin is used for the following applications:
• To study bacterial strains and growth conditions
• Used in short-term colony assays (the culture medium consists of hemin along with other components)
• Cell transfections
It may be used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.

Biochem/physiol Actions

Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.

Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.

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Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

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Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
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