Hemin
BioXtra, from Porcine, ≥98.0% (HPLC)
DOWNLOAD MSDS (PDF)Synonym:
Chloro(protoporphyrinato)
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CAS Number 16009-13-5
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Empirical Formula (Hill Notation) C34H32ClFeN4O4
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Molecular Weight 651.94
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Beilstein Registry Number 5229914
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EC Number 240-140-1
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MDL number MFCD00010726
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PubChem Substance ID 24873656
Properties
| Related Categories | Application Index, Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, Hemin, Metabolic Pathways, |
| biological source | from Porcine |
| product line | BioXtra |
| assay | ≥98.0% (HPLC) |
| storage temp. | 2-8°C |
Description
Frequently Asked Questions
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Biochem/physiol Actions
Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.
Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.
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