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51290 Sigma

Hemoglobin from bovine blood

lyophilized, 2×cryst., ≥90% (SDS-PAGE), powder

Synonym: Bovine hemoglobin, Hb, Methemoglobin

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Properties

Related Categories Biochemicals and Reagents, Bovine, Proteins and Derivatives More...
assay   ≥90% (SDS-PAGE)
form   powder
quality   2×cryst.
  lyophilized
mol wt   Mr ~64500
impurities   salt, none detected
  ~0.3% Fe
loss   ≤8% loss on drying
storage temp.   2-8°C
Gene Information   cow ... HBA1(281221), HBB(280813), HBE2(513240), HBE4(513108), HBG(511735), alpha globin(512439)

Description

Application

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Other Notes

Review: Oxygen carrier proteins

Sales restrictions may apply

Biochem/physiol Actions

Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

General description

Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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