• USA Home
  • 55155 - 7-Hydroxycoumarin-3-carboxylic acid

EMAIL THIS PAGE TO A FRIEND
55155 Sigma

7-Hydroxycoumarin-3-carboxylic acid

suitable for fluorescence, ≥98.0% (TLC)

Synonym: Umbelliferone-3-carboxylic acid

  • CAS Number 779-27-1

  • Empirical Formula (Hill Notation) C10H6O5

  • Molecular Weight 206.15

  •  Beilstein Registry Number 384141

  •  MDL number MFCD00017491

  •  PubChem Substance ID 57651515

Purchase

Properties

Related Categories Alphabetical, Analytical Reagents, Analytical/Chromatography, Biochemicals and Reagents, Detection,
InChI Key   LKLWLDOUZJEHDY-UHFFFAOYSA-N
assay   ≥98.0% (TLC)
pKa    7.04
mp   261 °C(lit.)
solubility   DMF: soluble
  DMSO: soluble
  alcohols: soluble
fluorescence   λex 342 nm; λem 447 nm (pH 4.0)
  λex 386 nm; λem 448 nm in 0.1 M Tris pH 9.0
suitability   suitable for fluorescence

Description

Other Notes

Immobilized on a support to give a pH sensor

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

7-Hydroxycoumarin-3-carboxylic acid (7-OHCCA) is used as a fluorogenic substrate for glycosyltransferase assays. 7-OHCCA may be used as a non-cinnamate-class substrate analog to study 4-hydroxycinnamate decarboxylase (4-HCD)-inducing activity in Klebsiella oxytoca cells.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Sensor Dyes

In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
Monika Baeumle
BioFiles 2011, 6.3, 23.
Keywords: Applications, Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Methods, Microscopy, Neurotransmission, Sol-gel, Type

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?