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55540 Sigma

4-(Hydroxymercuri)benzoic acid sodium salt

≥95.0% (Hg)

Synonym: p-Chloromercuribenzoate, p-Hydroxymercuribenzoic acid sodium salt, PCMB, Sodium 4-(hydroxymercurio)benzoate

  • CAS Number 138-85-2

  • Empirical Formula (Hill Notation) C7H5HgNaO3

  • Molecular Weight 360.69

  •  Beilstein Registry Number 6118796

  •  EC Number 205-340-5

  •  MDL number MFCD00002527

  •  PubChem Substance ID 57651536

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Properties

InChI Key   CBELQCYFTSHKPJ-UHFFFAOYSA-L
assay   ≥95.0% (Hg)
mp   ≥300 °C

Description

Application

4-(Hydroxymercuri)benzoic acid is an organic mercurial compound that reacts via mercury-sulfur affinity with sulfhydryl groups in peptides, proteins and other molecules. PCMB may be used for the determination of sulfhydryl groups in proteins according to Boyer, by atomic absorption, and stopped-flow measurements, G. Castronuovo-Lepore et al.. It may be used for specific applications such as probing the active site of an enzyme such as cytochrome C oxidase. 4-(Hydroxymercuri)benzoic acid appeared mistakenly as p-chloromercuriobenzoate [PCMB] in earlier literature.

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Suggested Laboratory Gloves


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Safety & Documentation

Safety Information

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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