Synonym: 4,5,7,4′,5′,7′-Hexahydroxy-2,2′-dimethylnaphthodianthrone, Cyclo werrol, Hypericum red
|Related Categories||Bioactive Small Molecules, Cell Biology, Glycosides, Including Glucosinolates, H, Hypericum perforatum (St John′s wort),|
Anthraquinone-derivative within St. John′s wort. Antibacterial effective against Gram-positive and Gram-negative bacteria.
Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones. Francesca Sorrentino et al Bioorg. Med. Chem. 19, 631-41, (2011)
Excited-state properties of hypericin: electronic spectra and fluorescence decay kinetics. Yamazaki, T., et al. J. Phys. Chem. 97, 7870-7875, (1993)
Mitochondria are a primary target of hypericin phototoxicity: synergy of intracellular calcium mobilisation in cell killing. Theodossiou, T.A., et al. Int. J. Biochem. Cell Biol. 38, 1946-1956, (2006)
Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy. Buytaert, E., et al. FASEB J. 20, 756-758, (2006)
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