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56968 Sigma

Sparfloxacin

≥98.0% (HPLC)

Synonym: 5-Amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Biochemicals and Reagents
biological source   from synthetic
InChI Key   DZZWHBIBMUVIIW-DTORHVGOSA-N
assay   ≥98.0% (HPLC)
form   powder
color   white
Mode of action   enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  mycobacteria
  mycoplasma
Gene Information   human ... KCNH1(3756), TOP2A(7153)

Description

Packaging

1g, 10g

Application

Sparfoxacin is used to study antimicrobial activity against Mycobacteria and respiratory tract infections .

Biochem/physiol Actions

Sparfloxacin fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. It inhibits bacterial DNA gyrase-dependent processes such as DNA polymerization, ATP-dependent-DNA supercoiling, and chromosome fragmentation.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
VB1986500
Protocols & Articles

Articles

HPLC Analysis of Antibiotics (Fluoroquinolones from Tablets) on Discovery® HS C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antibiotics (Fluoroquinolones from Tablets) on Discovery® HS C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Antibiotics on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antibiotics on Discovery® C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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