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61760 Sigma

Lectin from Canavalia ensiformis

lyophilized, ≥50% (GE), powder

Synonym: Agglutinin from jack beans, Con A

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Properties

assay   ≥50% (GE)
form   powder
quality   lyophilized
mol wt   Mr ~53000
storage temp.   2-8°C

Description

Biochem/physiol Actions

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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