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63559 Sigma

D-Mannitol

BioUltra, ≥99.0% (sum of enantiomers, HPLC)

Synonym: Mannite

  • CAS Number 69-65-8

  • Empirical Formula (Hill Notation) C6H14O6

  • Molecular Weight 182.17

  •  Beilstein Registry Number 1721898

  •  EC Number 200-711-8

  •  MDL number MFCD00064287

  •  PubChem Substance ID 57651947

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Properties

Related Categories Allium cepa (Onion), BioUltra, Biochemicals and Reagents, Carbohydrates, Cell Biology,
InChI Key   FBPFZTCFMRRESA-KVTDHHQDSA-N
product line   BioUltra
assay   ≥99.0% (sum of enantiomers, HPLC)
optical activity   [α]20/D +24.0±1° in borax solution acc. to Ph Eur
impurities   insoluble matter, passes filter test
  reducing sugars, complies
  ≤0.0072% free acid (as CH3COOH)
ign. residue   ≤0.01% (as SO4)
loss   ≤0.05% loss on drying, 20 °C (HV)
pH   5.0-6.5 (25 °C, 1 M in H2O)
mp   166-168 °C
  167-170 °C(lit.)
solubility   H2O: soluble1 M at 20 °C, clear, colorless
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤1 mg/kg
  Pb: ≤1 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   1 M in H2O
UV absorption   λ: 260 nm Amax: 0.04
  λ: 280 nm Amax: 0.04

Description

Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Other Notes

Used in discontinuous gradient centrifugation for purification of plant protoplasts. Plasmolyticum that reversibly inhibits phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM. Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers.

Application

D-Mannitol is used as an osmolyte and transport facilitator in a variety of biological in vivo and in vitro applications, such as improvement of blood-brain barrier transport and hyperosmolar therapy. D-Mannitol is used as a substrate to identify, differentiate and characterized enzymes such as mannitol dehydrogenase(s). D-Mannitol is used in identify mannitol metabolizing bacteria.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
OP2060000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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