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70485 Sigma

Naphthol AS-E phosphate

for histology

Synonym: KG-501

  • CAS Number 18228-17-6

  • Empirical Formula (Hill Notation) C17H13ClNO5P

  • Molecular Weight 377.72

  •  Beilstein Registry Number 6664478

  •  EC Number 242-106-1

  •  MDL number MFCD00042718

  •  PubChem Substance ID 329762485

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Properties

Related Categories Acid Phosphatase, Alkaline Phosphatase, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates,
grade   for histology
InChI Key   RQAQWBFHPMSXKR-UHFFFAOYSA-N
storage temp.   2-8°C

Description

Other Notes

Histochemical substrate for alkaline phosphatases,KG-501 blocks cAMP-induction of CREB (cAMP Response Element Binding Protein)-dependent target gene transcription (Ki 10 microM)) through interference in the binding between the KID domain of CREB and KIX domain of CBP (CREB Binding Protein), classic activator-coactivator interaction.

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Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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