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71162 Sigma

Naringin

≥95% (HPLC)

Synonym: 4′,5,7-Trihydroxyflavanone 7-rhamnoglucoside, Naringenine-7-rhamnosidoglucoside

  • CAS Number 10236-47-2

  • Empirical Formula (Hill Notation) C27H32O14

  • Molecular Weight 580.53

  •  Beilstein Registry Number 102012

  •  EC Number 233-566-4

  •  MDL number MFCD00148888

  •  PubChem Substance ID 57652274

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Properties

Related Categories Cell Biology, Hematology and Histology, Natural Dyes, Stains and Dyes
InChI Key   DFPMSGMNTNDNHN-JJLSSNRUSA-N
assay   ≥95% (HPLC)
optical activity   [α]20/D −80±10°, c = 1% in ethanol

Description

Biochem/physiol Actions

Naringin, a flavanoid in grapefruit and other citrus fruits, potently inhibits intestinal organic anion-transporting polypeptide 1A2 (OATP1A2). Grapefruit juice thereby reduces bioavailability of many pharmacological agents taken at the same time.

Price and Availability


Tissue Diagnostics

All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
QN6340000
Protocols & Articles

Articles

HPLC Analysis of Grapefruit Juice on Ascentis® Express C18 Column

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Grapefruit Juice on Ascentis® Express C18 Column
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Sample preparations, Solid phase extractions

Peer-Reviewed Papers
15

References

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