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72340 Sigma

Nicotinamide

≥99.5% (HPLC)

Synonym: Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP

  • CAS Number 98-92-0

  • Empirical Formula (Hill Notation) C6H6N2O

  • Molecular Weight 122.12

  •  Beilstein Registry Number 383619

  •  EC Number 202-713-4

  •  MDL number MFCD00006395

  •  PubChem Substance ID 57652413

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Properties

Related Categories Aloe Vera, Biochemicals and Reagents, Carthamus tinctorius (Safflower oil), Cell Biology, Hypericum perforatum (St John′s wort),
InChI Key   DFPAKSUCGFBDDF-UHFFFAOYSA-N
assay   ≥99.5% (HPLC)
form   powder or crystals
ign. residue   ≤0.2%
loss   ≤0.2% loss on drying, 20 °C (HV)
mp   128-131 °C(lit.)
  128-131 °C
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤100 mg/kg
cation traces   Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
Gene Information   human ... PARP1(142), SIRT2(22933)

Description

Other Notes

Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes

Biochem/physiol Actions

Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule.

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Price and Availability

Suggested Laboratory Gloves


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
QS3675000
Flash Point(F) 
302 °F
Flash Point(C) 
150 °C
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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Description

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762970 Nicotinamide-2,4,5,6-d4, 98 atom % D, 98% (CP)

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